RNA Details
Disease Name
myocardial infarction
Tissue
heart
RNA Symbol
PFN2
RNA ID
RNA Type
mRNA
Alteration Pattern
up regulation
Species
homo sapiens
Detection Methods
dual-luciferase reporter assay
Target
MIR-378;GRB2
Pathway
NA
PubMed ID
Title
LncRNA PCFL promotes cardiac fibrosis via miR-378/GRB2 pathway following myocardial infarction
Year
2019
Function
"PCFL, and the mechanism involves the direct interaction of PCFL with miR-378, which in turn relieves the inhibition effect of miR-378 on GRB2 and promotes cardiac fibrosis."